Ace Therapeutics provides comprehensive support for the testing and analysis of H. pylori drugs, and we offer general testing services for H. pylori drugs, including quality testing, toxicity testing, and stability testing. We offer customized testing services based on the type of drug and its manufacturing status.
Quality testing of H. pylori drugs
Our quality testing for H. pylori drugs includes three aspects, namely identity verification, purity assessment, and impurity detection. And we offer individualized quality testing for H. pylori drugs, including small molecule drugs, peptide and protein drugs, and polysaccharide drugs.
For H. pylori small molecule drugs, we use nuclear magnetic resonance (NMR), infrared spectroscopy (IR), mass spectrometry (MS), and optical rotation spectroscopy (ORD) for identity verification and impurity detection, and then use the detection data for purity analysis.
For H. pylori peptide and protein drugs, we use X-ray crystallography, NMR, frozen electron microscopy, small-angle scattering (SAS), and microcrystalline electron diffraction (MicroED) to identify the structure of peptide and protein drugs. Then, we use in vitro or in vivo activity assays to evaluate the number of active molecules. As for impurity detection, we first use physical and chemical methods such as electrophoresis and chromatography for impurity analysis, and then we use biological methods to detect impurities that require special analysis, such as bacterial residue detection, non-target peptide and protein detection, and harmful biological substances detection.
For H. pylori polysaccharide drugs, we use NMR, ourier transform infrared spectroscopy (FT-IR), ultraviolet spectrophotometry (UV), gas chromatography-mass spectrometer (GC-MS), pulsed amperometric detection (PAD), and other methods for the structural identification of polysaccharides and impurity analysis. In addition, we also provide services for the composition and content analysis of extracted polysaccharides. For example, we offer composition and content analysis of extracted okra polysaccharides that have inhibitory effects on the adhesion of H. pylori to gastric epithelial cells.
Learn more: h pylori drug toxicity testing
