Neoantigens, which are tumor-specific antigens derived from nonsynonymous mutations, are very attractive targets for tumor immunotherapy. Thanks to the development of next-generation sequencing technologies and the application of machine learning algorithms, it has become possible to computationally predict neoantigens by characterizing genetic alterations, aberrant post-transcriptional mRNA processing, and aberrant mRNA translation events within tumor tissues. Learn more:
neoantigen vaccines synthesis